evaluation of oogenesis aspects in neonatal and adult mice after toloaldoxime treatment
نویسندگان
چکیده
objective: oximes are important materials in organic chemistry. synparamethyl benzaldehyde oxime (toloaldoxime) is structurally similar to other oximes, hence we have studied its effects on the neonatal and adult female balb/c mice reproductive systems in order to provide a platform for future studies on the production of female contraceptive drugs. materials and methods: in experimental study, we studied the effects of toloaldoxime on ovary growth and gonadal hormones of neonatal and adult balb/c mice. a regression model for prediction was presented. results: the effects of toloaldoxime on neonatal mice were more than adult mice. the greatest effect was on the number of graafian follicles (59.6% in adult mice and 31.83% in neonatal mice). the least effect was on ovary weight, and blood serum levels of follicle stimulating hormone (fsh) and luteinizing hormone (lh). conclusion: according to the data obtained, toloaldoxime can be considered an antipregnancy substance.
منابع مشابه
Evaluation of Oogenesis Aspects in Neonatal and Adult Mice after Toloaldoxime Treatment
OBJECTIVE Oximes are important materials in organic chemistry. Synparamethyl benzal- dehyde oxime (toloaldoxime) is structurally similar to other oximes, hence we have studied its effects on the neonatal and adult female Balb/c mice reproductive systems in order to provide a platform for future studies on the production of female contraceptive drugs. MATERIALS AND METHODS In experimental stud...
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عنوان ژورنال:
cell journalجلد ۱۷، شماره ۳، صفحات ۵۶۴-۵۶۸
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